Isolation and identification of antibacterial compound from common name Holothuria leucospilota in the Persian Gulf
- سال انتشار: 1399
- محل انتشار: مجله علوم شیلات ایران، دوره: 19، شماره: 5
- کد COI اختصاصی: JR_JIFRO-19-5_021
- زبان مقاله: انگلیسی
- تعداد مشاهده: 234
نویسندگان
Persian Gulf and Oman Sea Ecological Research Center, Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research, Education and Extension Organization (AREEO), Bandar Abbas, Iran
Iranian Fisheries Research Institute (IFSRI), Agricultural Research, Education and Extension Organization (AREEO), Tehran, Iran
Persian Gulf and Oman Sea Ecological Research Center, Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research, Education and Extension Organization (AREEO), Bandar Abbas, Iran
Persian Gulf and Oman Sea Ecological Research Center, Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research, Education and Extension Organization (AREEO), Bandar Abbas, Iran
Persian Gulf and Oman Sea Ecological Research Center, Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research, Education and Extension Organization (AREEO), Bandar Abbas, Iran
Iranian Fisheries Research Institute (IFSRI), Agricultural Research, Education and Extension Organization (AREEO), Tehran, Iran
چکیده
Echinodermata are one of the most important branches of invertebrate in marine ecosystems, which today are also known as a rich source of natural products with biological properties. Most of these properties belong to compounds with a terpenoids structure. According to the biological properties of sea cucumbers in the Persian Gulf, this scientific study investigates the antibacterial properties of lanosterol compounds extracted from Holothuria leucospilota in Hengam Island in the Persian Gulf. The sea cucumber powder was extracted using acetone, then the extract purified by silica gel column chromatography with n-hexane and ethyl acetate combination to isolate the terpenoid compounds. Isolated compound were run through TLC and sprayed with vanillin-sulphuric acid reagent for detection of terpenoid compounds and profile of isolated compounds obtained by gas chromatography (GC). The lanosterol teriterpenoids compound in column fraction was identified by GC. Antimicrobial properties were evaluated by dilution test on bacterial strain Escherichia coli, Pseudomonas aeruginosa, Klebsiella nemonya, Proteus vulgaris, Salmonella typhi, Staphylococcus aureus, Bacillus subtilis, Bacillus cereus and Nocardia brazilinus. This compound show antibacterial activities against gram-positive bacteria (B. subtilis, B. cereus and S. aureus). Antibacterial results of lanosterol authenticated that could be an efficacious compound in antibiotics productionکلیدواژه ها
Natural products, Terpenoids, Antibacterial, Hengam Island, Persian Gulfاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.