Allergic Rhinitis in Adults with Chronic Suppurative Otitis Media

  • سال انتشار: 1394
  • محل انتشار: مجله علمی گوش و حلق و بینی ایران، دوره: 27، شماره: 4
  • کد COI اختصاصی: JR_IJOTO-27-4_002
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 340
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نویسندگان

Shadman Nemati

Sinonasal Diseases Research Centre, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran.

Reza Jafari Shakib

Department of Immunology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Maryam Shakiba

PhD Candidate, Department of Epidemiology, School of Public Health, Shahid Beheshti University of medical sciences, Tehran, Iran.

Nematollah Araghi

Department of Otolaryngology, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran.

Seyyede Zeinab Azimi

Sinonasal Diseases Research Centre, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran.

چکیده

Introduction: Chronic suppurative otitis media (CSOM) is considered one of the most common causes of acquired hearing impairment in developing countries. CSOM is a multifactorial persistent inflammatory disease of the middle ear. A distinct pathophysiologic mechanism linking allergic rhinitis (AR) and CSOM remains to evolve. The purpose of this study was to investigate the association between AR and CSOM in adults.This was a case-control study.   Materials and Methods: The subjects were ۶۲ adults (۲۳ male, ۳۹ female) with established CSOM and ۶۱ healthy controls.CSOM was diagnosed when there was a history of chronic (persisting for at least ۳ months) otorrhea, accumulation of mucopurulent exudates in the external auditory canal or middle ear and/or perforated tympanic membrane on otoscopy. All participants were evaluated for the presence of AR by clinical evaluation of allergic symptoms, and underwent a skin-prick test for ۲۳ common regional allergens. Statistical analysis was performed using SPSS version ۱۶.   Results: The prevalence of clinical rhinitis (allergic and non-allergic) was significantly higher among the cases compared with controls (۶۲.۵% vs. ۳۷.۵%, P=۰.۰۲). The prevalence of AR (proven by positive skin-prick test) was also significantly higher among affected adults than controls (۲۴.۶% and ۱۳.۸%, respectively). Adjusting for age, a logistic regression model showed that there was a significant difference between the two groups. Patients with AR and non-AR were at ۳.۲۷- (۹۵% CI=۱.۱۵–۹.۲۹; P=۰.۰۳۶) and ۲.۵۷-(۹۵% CI=۱.۰۱–۶.۵۷; P=۰.۰۴۸) fold increased risk of developing CSOM, respectively, compared with healthy individuals.   Conclusion:  The study showed a higher prevalence of AR in CSOM patients than in controls. It may be valuable to evaluate and control this factor in these patients.  

کلیدواژه ها

Rhinitis, Allergic, Hypersensitivity, Otorhinolaryngologic diseases, Otitis media, Suppurative, Skin test

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