Antimicrobial impacts of methanolic extract of Cyanobacteria isolated from Iran's Lake Urmia

سال انتشار: 1400
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 220

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شناسه ملی سند علمی:

BMPM04_042

تاریخ نمایه سازی: 22 آذر 1400

چکیده مقاله:

Cyanobacteria, as a rich source of bioactive compounds, has been potentially considered for biomedical and pharmaceutical applications. In the present study, isolation and identification of Chroococcus turgidus were performed from the south of Lake Urmia. The crude metabolites were extracted from Ch. turgidus biomass according to the soxhlet method using methanol. The methanol extract (ME) were concentrated in a rotary evaporator, followed by removing the traces of solvent with the desiccator. The disk diffusion and broth microdilution methods were used to determine the antimicrobial effects and the minimum inhibitory concentration, respectively. According to the inhibition zone, the ME showed a significant effect on the Enterobacteriaceae family, which are commonly involved in different gastrointestinal infections. In conclusion, the Ch. turgidus extract can introduce various compounds as suitable candidates for developing new antimicrobial agents

نویسندگان

Hamieh Goshtasbi

Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.Department of Plant Biology, Faculty of Natural Science, University of Tabriz, Tabriz, Iran.

Azam Safary

Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Mostafa Akbarzadeh-Khiavi

Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Ali Movafeghi

Department of Plant Biology, Faculty of Natural Science, University of Tabriz, Tabriz, Iran.

Yadollah Omidi

College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, USA.