Medical Evaluation of Test Results Related to Covid ۱۹ in Iranian Hospitals Using QUADAS-۲ to Evaluate the Quality of Studies and Meta-Analysis Using Stata / MP v.۱۶ Software

  • سال انتشار: 1401
  • محل انتشار: مجله علوم دارویی و شیمی، دوره: 5، شماره: 2
  • کد COI اختصاصی: JR_JMCH-5-2_010
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 303
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نویسندگان

Hoseinali Danesh

Plastic, Reconstructive & Aesthetic Surgeon, Assistant Professor of Zahedan University of Medical Sciences (ZAUMS)

Saeid Rahimi Ghasabeh

Anesthesiologist at Noor Afshar hospital, Iranian Red Crescent Society, Iran

Ramin Rounasi

Department of Anesthesiology and Pain Medicine, Iran University of Medical Sciences, Tehran, Iran

Ehsan Zarepur

Resident of cardiology, Isfahan cardiovascular research center, Isfahan cardiovascular research institute, Isfahan University of Medical Sciences, Isfahan, Iran

Ali Abdolrazaghnejad

Clinical Immunology Research Center at Zahedan University of Medical Sciences, Zahedan, Iran

چکیده

The aim of current study was to evaluate the outcome of some laboratory tests and accuracy of diagnostic tests for patients with COVID-۱۹. The QUADAS-۲ tool was utilized to quality assessment of diagnostic accuracy studies. For data extraction, two reviewers blind and independently extracted data from abstract and full text of studies that included. ۹۵% confidence interval for effect size with fixed effect model and Inver-variance method were calculated. Meta-analysis was performed using Stata/MP v.۱۶ software. ۴۶۹ studies were reviewed, of which the full text of ۵۲ studies was reviewed and finally twenty-two studies were selected for meta-analysis.  Mean differences of Alanine transaminase was ۳.۴۰ U/L (MD, ۹۵% CI -۲.۴۵, ۹.۲۵), correlation between Alanine transaminase and severe COVID-۱۹ was not significantly. Stool, feces, rectal swabs ۲۵% (ES, ۹۵% CI ۰.۳۲, ۰.۸۲), Urine ۱% (ES, ۹۵% CI ۰.۰۵, ۰.۵۸), overall sensitivity of PCR for detection of COVID-۱۹ was ۴۴% (ES, ۹۵% CI ۰.۱۹, ۰.۶۸), less sensitive observerd when PCR detection of COVID-۱۹.  Evidence revealed that at the time of admission of patients with COVID-۱۹, a specific laboratory model can be used to perform relevant tests and make decisions about patients. PCR using sputum samples was highly sensitive for detecting COVID-۱۹ and after that computed tomography of the chest was identified with high sensitivity.

کلیدواژه ها

Laboratory tests, diagnostic tests, COVID-۱۹, PCR

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