Prevalence of Cognitive Impairment and Its Associated Factors in Elderly Patients under Chronic Hemodialysis Treatment

  • سال انتشار: 1400
  • محل انتشار: مجله علوم دارویی و شیمی، دوره: 4، شماره: 6
  • کد COI اختصاصی: JR_JMCH-4-6_013
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 316
دانلود فایل این مقاله

نویسندگان

Raheleh Alimoradzadeh

Firoozabadi Clinical Research Development Unit (FACRDU), Iran University of Medical Sciences (IUMS), Tehran, Iran

Hosna Ranjbar

Iran University of Medical Sciences, Tehran, Iran

Mohammad Amin Abbasi

Firoozabadi Clinical Research Development Unit (FACRDU), Iran University of Medical Sciences (IUMS), Tehran, Iran

Fatemeh Montazer

Firoozabadi Clinical Research Development Unit (FACRDU), Iran University of Medical Sciences (IUMS), Tehran, Iran

چکیده

The present study was a cross-sectional investigation carried out on elderly patients under chronic hemodialysis who referred to Firoozabadi Hospital during ۲۰۱۹- ۲۰۲۰. The study population was ۸۰ patients ≥ ۶۰ years. The patients’ cognitive status was determined using MMSE and MOCA tools. The mean age of the candidate patients was ۷۱.۷۱ ± ۶.۲۸ years old. Cognitive function was assessed by MMSE and MoCA tests and the mean score of the MMSE test was ۲۰.۰۵ ± ۳.۵۰ with the highest score being ۲۶ and the lowest score being ۱۲. Based on the results, these patients were divided into three groups with normal cognitive ­function, mild cognitive impairment, and severe cognitive impairment. According to the results of the MMSE test, ۱۹ patients (۲۳.۷۵%) had a normal cognitive function and ۴۵ patients (۵۶.۲۵%) had impairment. In other words, the older patients, the lower level of education, the longer duration of hemodialysis, and the patients with a history of diabetes were more susceptible to cognitive impairment. Subsequently, there was a positive correlation between the levels of BUN, creatinine, uric acid, and PTH, which means that the higher level of these variables in patients was related to the higher risk of cognitive impairment. The findings of the present investigation revealed that the cognitive function and the studied variables including age, level of education, history of diabetes, hemodialysis duration, BUN, Creatinine, Uric Acid, PTH, Sodium, and Kt/V had a significant difference in patients undergoing hemodialysis. 

کلیدواژه ها

Elderly, Chronic hemodialysis, Cognitive Impairment, Diabetes

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.