Sunil Gaikwad - Department of Chemistry, Centre for Advanced Research, Savitribai Phule Pune University, Pune ۴۱۱۰۰۷, India
Milind Gaikwad - Department Of Chemistry, Dr. D. Y. Patil A.C.S. College, Pimpri, Savitribai Phule Pune University Pune- ۴۱۱۰۱۸, India
Pradeep Lokhande - ۱Department of Chemistry,a Centre for Advanced Research, Savitribai Phule Pune University, Pune ۴۱۱۰۰۷, India

AbstractWe have developed a simple method for the regioselective aromatization of Polysubstituted Cyclohexanone derivatives in the presence of iodine (۲۵ mol %), Pd/C (۱۰Mol%) in dimethyl sulfoxide at ۹۰ °C. , afforded functionalized biphenyls with at least one phenolic hydroxyl in moderate to very good yields. The present protocol contains a cheap catalyst, easy work up, normal reaction conditions, and high selectivity.

Molecular iodine, DMSO, Pd/C, Biaryl phenol, multi substituted cyclohexanone