Congenital Heart Defects in Children with Upper Gastrointestinal Anomalies
- سال انتشار: 1400
- محل انتشار: مجله علمی ناباروری ایران، دوره: 12، شماره: 4
- کد COI اختصاصی: JR_IRJN-12-4_008
- زبان مقاله: انگلیسی
- تعداد مشاهده: 222
نویسندگان
Hassan Mottaghi Moghaddam Shahri
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Pediatrics, Mashhad university of Medical Sciences, Mashhad, Iran
Department of Pediatrics, Mashhad university of Medical Sciences, Mashhad, Iran
Mashhad Universi of Medical sciences, Mashhad, Iran
Akbar Clinical Research and Development Unit, Mashhad University of Medical Sciences, Mashhad, Iran
چکیده
Background: Congenital heart defect (CHD) is one of the leading causes of neonatal death. Although the majority of CHDs are isolated, a significant number of them are associated with noncardiac anomalies. Esophageal Atresia (EA)/ Tracheoesophageal Fistula (TEF) is the most common congenital disorder of the upper GI tract. It is estimated that up to ۷۰% of EA/TEF infants have other associated congenital anomalies such as CHD. This study determined the proportion of heart anomalies among the diseases of the upper GI tract in Imam Reza Hospital of Mashhad. Methods: The records of ۳۸ infants with upper GI obstruction who were referred to the Pediatric Cardiology Clinic of Imam Reza Hospital in Mashhad between ۲۰۰۱ and ۲۰۱۷ were evaluated in this retrospective study. Data were coded and entered into SPSS software (version ۱۶) and analyzed using Chi-square and T-test. Results: In this study, ۳۸ babies with upper GI obstruction were evaluated (۲۰ patients were female, ۵۲.۶%), and the average birth weight was ۲.۳۹۰ +-۰.۸۷۰ gr. Among the parents, ۱۳ patients (۳۴.۲%) were relative (third-degree or more) and ۲۵ patients (۶۵.۸%) were nonrelative. The initial and final diagnosis was different at ۱۴ pt (۳۶.۸%) that was confirmed with echocardiographic findings. CHDs were divided into two groups in this study. Malformations such as PFO (patent foramen ovale) or FMV without MR (floppy mitral valve without mitral regurgitation) considered as non-important congenital heart diseases. Other malformations that require interventional or medical management such as VSD, ASD, TOF, or other CHDs are considered important CHDs. Nineteen pt (۵۰%) had important CHD and ۱۶ pt (۴۲.۱%) had non-important CHD and ۳ pt (۷.۹%) had normal echocardiographic findings. Conclusion: The heart defect is the most common associated anomaly in children with EA/TEF, which is divided into two subgroups. The first important one is CHD, which is effective in gastric surgery and management, and VSD is the most common type. The other group is non important CHD such as PFO or FMV without MR that are not effective in their management. The patients with EA/TEF are at risk for low birth weight and preterm delivery.کلیدواژه ها
cardiac malformation, Congenital disorder, Esophageal atresia, neonate, tracheoesophageal fistulaاطلاعات بیشتر در مورد COI
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