Fabrication and characterization of co-electrospun polycaprolactone/chitosan nanofibrous mats

  • سال انتشار: 1399
  • محل انتشار: سومین کنفرانس دوسالانه نفت، گاز و پتروشیمی خلیج فارس
  • کد COI اختصاصی: OGPC03_079
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 325
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نویسندگان

Shahnoosh Afshar

Department of Polymer Engineering, Islamic Azad University-Mahshahr Branch, Khuzestan, Iran

Shiva Rashedi

Department of Polymer Engineering, Amirkabir University of Technology-Mahshahr Campus, Khuzestan, Iran

Amir Rostami

Department of Chemical Engineering, Faculty of Petroleum, Gas, and Petrochemical Engineering, Persian Gulf University, Bushehr, Iran

Hossein Nazockdast

Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, Tehran, Iran

Malihe Ghazalian

Department of Textile Engineering, Amirkabir University of Technology, Tehran, Iran

چکیده

Core-shell nanofibers were fabricated via coaxiall electrospinning using polycaprolactone (PCL) as the shell material and chitosan (CS) as the core material. The confirmation of core-shell structure of the electrospun nanofibers was performed by attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and Water Contact Angle (WCA) measurements. The obtained results of FTIR showed that the surface of the core-shell nanofibers is uniformly covered with PCL, and CS was successfully encapsulated by PCL. The Morphological investigation was done by scanning electron macroscopy (SEM) which showed bead-free ultrafine CS-PCL core-shell nanofibers. PCL composition in the as-spun core-shell nanofibers was determind by DSC analysis based on the latent heat of PCL which was ۶۴.۳%. In vitro degradation test showed that because of the presence of core material, the fibrous structure of core-shell mat was maintained and prevented from the collapse of structure. The fabricated CS-PCL core-shell nanofibers have potentials in some biomedical applications.

کلیدواژه ها

Chitosan,Polycaprolactone,Electrospinning,Core-shell nanofibers,

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