Reyhaneh Ghasemi Eshkaftaki - D.V.M grauated in Veterinary course, Shahrekord University, Shahrekord, Iran,
Sulmaz Tarakameh Samani - Graguated in Small animal internal medicine course of veterinary medicine, Shahid Chamran University,Ahwaz, Iran,
Majid Zakerian - Graguated in Small animal internal medicine course of veterinary medicine, Shahid Chamran University,Ahwaz, Iran,

Spirocercosis is caused by the nematode Spirocerca lupi in dogs. Because of side effects of Ivermectin injection, daily as most routine cheical treatment of spirocerca lupi in dogs such as shock like reaction and digestive signs such as stomach pain and vomting, so our aim is to replace dianthus caryophyllus and ginseng as herbal medicines of Iran.۱۵ dogs which infected with Spirocerca lupi used in this experiment. They were divided in three groups of ۵ members. In one group (control group), they were treated by surgical treatment and ivermectin injection, daily as ۰.۵ ml upto ۹۰ days. In second group after surgical treatment they were fed diets containing ۱۵ mg/kg body weight/day ginseng autoclaved powdered extract to assess its effect on immunological activity for ۹۰ consecutive days. In third group after surgical treatment they were fed diets containing ۱۵ mg/kg body weight/day dianthus caryophyllus autoclaved poweder extract to assess its effect on immunological activity for ۹۰ consecutive days.In current report, all results proved that none of dogs which treated with ginseng or dianthus caryophyllus had relapses of disease and fecal examination didn’t show any eggs.

Ivermectin, dianthus caryophyllus , Ginseng, Spirocercosis, dog.