The effects of whole green tea infusion on mouse urinary bladder chemical carcinogenesis

  • سال انتشار: 1393
  • محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 17، شماره: 2
  • کد COI اختصاصی: JR_IJBMS-17-2_012
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 124
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نویسندگان

Andreia Henriques

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

Regina Arantes-Rodrigues

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

Ana I Faustino-Rocha

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

Catarina I Teixeira-Guedes

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

Jacinta Pinho-Oliveira

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

Daniela Talhada

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

José H Teixeira

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

Andreia Andrade

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

Bruno Colaço

Department of Zootechnics, University of Trás-os-Montes and Alto Douro, ۹۱۱ Vila Real, Portugal Center for the Study of Animal Sciences (CECA), University of Porto, ۴۴۸۵-۶۶۱, Porto, PortugalCentre for the Research and Technology

Maria N Paiva-Cardoso

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, Portugal

Maria J Pires

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, PortugalCenter for the Study of Animal Sciences (CECA), University of Porto, ۴۴۸۵-۶۶۱, Porto, PortugalCentre for the Research and

Ana MVD Ferreira

Chemistry Research Center, CQ-VR, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۸۰۱, Vila Real, Portugal

Fernando M Nunes

Chemistry Research Center, CQ-VR, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۸۰۱, Vila Real, Portugal

Paula A Oliveira

Department of Veterinary Sciences, ECAV, University of Trás-os-Montes and Alto Douro, ۵۰۰۱-۹۱۱, Vila Real, PortugalCenter for the Study of Animal Sciences (CECA), University of Porto, ۴۴۸۵-۶۶۱, Porto, PortugalCentre for the Research and

چکیده

Objective(s):Green tea (GT) is one of the most popular beverages worldwide whose beneficial effects on health have been demonstrated. Recent studies suggest that GT may contribute to reduction of cancer risk and progression. The aim of this study was to evaluate the effects of whole GT on urinary bladder chemical carcinogenesis in male and female ICR mice. Materials and Methods: The GT characterization was performed using spectrophotometric methods. Urinary bladder lesions were induced using N-butyl-N-(۴-hydroxybutyl) nitrosamine (BBN) by gavage during ۱۰ weeks and whole GT (۰.۵%) was provided ad libitum during ۲۰ weeks. Results:Animals from groups BBN+GT and BBN only developed preneoplastic lesions. Conclusion:We did not observe any effects by GT infusion administration on urinary bladder cancer development.

کلیدواژه ها

green tea, Mice, N-butyl-N-(۴-hydroxybutyl)nitro- samine, Urinary bladder cancer

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