Berberis vulgaris for cardiovascular disorders: a scoping literature review
- سال انتشار: 1396
- محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 20، شماره: 5
- کد COI اختصاصی: JR_IJBMS-20-5_008
- زبان مقاله: انگلیسی
- تعداد مشاهده: 226
نویسندگان
Faculty of Medicine, Ain Shams University, Cairo, Egypt
Faculty of Medicine, Ain Shams University, Cairo, Egypt
Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia ۴۱۵۲۲, Egypt
چکیده
Cardiovascular disorders are the leading cause of mortality worldwide. Berberis vulgaris (B. vulgaris) is a commonly used plant in traditional medicine. In recent studies, B. vulgaris showed antiarrhythmic, antihypertensive, anticholinergic, and cardioprotective effects. We reviewed the literature to explore the possible prophylactic and therapeutic roles of B. vulgaris in cardiovascular medicine. A computer literature search was conducted to identify all relevant studies that have investigated the role of B. vulgaris in prevention or treatment of cardiovascular diseases.We also searched the citations of the retrieved articles. Using a systematic approach, we conducted a scoping review that included a total of ۳۷ articles. Twelve studies examined the antihypertensive effects of B. vulgaris, seven studies investigated its antiarrhythmic effects, while its inotropic and cardioprotective effects were evaluated in four and eight studies, respectively. B. vulgaris showed a beneficial effect in reducing blood pressure, enhancing cardiac contractility, and protection from reperfusion injury. However, the mechanisms of these effects are still under investigation. Moreover, it could modify major risk factors for cardiovascular disorders, such as oxidative stress, hyperglycemia, and hyperlipidemia. Further studies are needed to translate these findings into effective cardiovascular medications.کلیدواژه ها
Antiarrhythmic, Antihypertensive, Berberis vulgaris, Cardioprotective Cardiovascularاطلاعات بیشتر در مورد COI
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