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Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review

عنوان مقاله: Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review
شناسه (COI) مقاله: JR_IJBMS-20-6_001
منتشر شده در در سال 1396
مشخصات نویسندگان مقاله:

Fatemeh Ayoobi - Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Ali Shamsizadeh - Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Iman Fatemi - Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Alireza Vakilian - Geriatric Care Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Mohammad Allahtavakoli - Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Gholamhossein Hassanshahi - Pistachio Safety Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
Amir Moghadam-Ahmadi - Department of Neurology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

خلاصه مقاله:
The Achillea millefolium L. (Yarrow) is a common herb which is widely being used, worldwide. Achillea is being used for treatment of many disorders since centuries. It is considered safe for supplemental use and flavonoids such as kaempferol, luteolin and apigenin are of main constituents present in Achillea. Most of both antioxidant and anti-inflammatory properties of this herb have been attributed to its flavonoid content. Oxidative and inflammatory processes play important roles in pathogenesis of neurodegenerative diseases. Present review was aimed to review the latest literature evidences regarding application of Achillea and/or its three main flavonoid constituents on epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease and stroke.

کلمات کلیدی:
Achillea millefolium, Flavonoids, Medicinal, Neurodegenerative disease, Plants

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1295704/