An Investigation into the CSF Absorption in Cats
محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 10، شماره: 4
سال انتشار: 1387
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 159
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شناسه ملی سند علمی:
JR_IJBMS-10-4_007
تاریخ نمایه سازی: 27 مهر 1400
چکیده مقاله:
Objective Cerebrospinal fluid (CSF), its secretion, circulation and absorption have been the subject of recent researches. There is a general agreement that the main site of CSF secretion is in the choroids plexus. However, the main absorption site is controversial. Some believe that arachnoid granulations are the principle sites of CSF absorption. In this study, different locations of CSF absorption in cats are investigated. Materials and Methods ۲ ml (۱۰۰ mg), of ferrous dextran was injected into the subarachnoid compartment of seven cats. After ۱۵ days the animals were euthanized, and the central nervous system (CNS) and its relative tissues were analyzed for any iron amlumulation. Several tissue samples were taken and stained with Prussian blue and Hematoxylin-eosin. Results The light microscopic study of different tissues showed amlumulation of the tracer in olfactory and optic nerves, dorsal root ganglia as well as spinal nerve roots. Conclusion The main locations of CSF absorption were the spinal nerve roots and their surrounding lymphatic tissue. There is reason to believe that some endothelial fenestrate within these roots were involved in this process.
کلیدواژه ها:
نویسندگان
Karim Nikkhah
Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran
Reza Sadrenabavy
Department of Neurology, MUMS, Mashhad, Iran
Payam Sasannezhad
Department of Neurology, MUMS, Mashhad, Iran
Ali Shoeibi
Department of Neurology, MUMS, Mashhad, Iran
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