Fabrication, Characterization and Osteoblast Response of Cobalt-Based Alloy/Nano Bioactive Glass Composites
- سال انتشار: 1395
- محل انتشار: فصلنامه مواد پیشرفته و فرآوری، دوره: 4، شماره: 3
- کد COI اختصاصی: JR_JMATPR-4-3_001
- زبان مقاله: انگلیسی
- تعداد مشاهده: 209
نویسندگان
Department of Materials Science and Engineering, Faculty of Engineering, University of Kashan, Kashan, I.R. Iran
Department of Materials Engineering, Isfahan University of Technology (IUT), Isfahan ۸۴۱۵۶-۸۳۱۱۱, Iran
Department of Materials Engineering, Isfahan University of Technology (IUT), Isfahan ۸۴۱۵۶-۸۳۱۱۱, Iran
چکیده
IIn this work, cobalt-based alloy/ nano bioactive glass (NBG) composites with ۱۰, ۱۵ and ۲۰ wt% NBG were prepared and their bioactivity after immersion in simulated body fluid (SBF) for ۱ to ۴ weeks was studied. The scanning electron microscopy images of two- step sintered composites revealed a relatively dense microstructure the density of which decreased with the increase in the NBG amount. Microstructural analysis as well as energy dispersive X-ray analysis (EDX) revealed that after ۱ week of immersion in SBF, a small amount of calcium phosphate phases precipitates on the surface of the composite samples. After ۲ weeks of immersion, a considerable amount of cauliflower-like shaped precipitations was observed on the surface of composites. The observed peaks in the Fourier transform infrared (FTIR) spectroscopy of the composite samples in SBF immersed for ۴ weeks were assigned to hydroxyapatite. Therefore, a hydroxyapatite layer has been possibly formed on the surface of the composite samples during immersion in SBF. Cell culture results indicate that unlike the Co-based alloy, the Co-based/NBG composites are bioactive and bone cells could be vivid and grow on their surfaces, promising their possibility for implant applications.کلیدواژه ها
Biomaterials, Sintering, Nano bioactive glass Response Surface, Osteoblast responseاطلاعات بیشتر در مورد COI
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