Investigation of Helicobacter pylori infections and lifestyle factors in patients in Mashhad

  • سال انتشار: 1400
  • محل انتشار: بیست دومین کنگره میکروب شناسی ایران (مجازی)
  • کد COI اختصاصی: MEDISM22_359
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 212
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نویسندگان

SeyedeShahrzad Mahroughi

Department of biology, faculty of science, Ferdowsi university of Mashhad

Mohammadreza Sharifmoghadam

Department of biology, faculty of science, Ferdowsi university of Mashhad

Leila Shokrzade

Ph.D. graduated, Alzahra university

Masoume Bahreini

Department of biology, faculty of science, Ferdowsi university of Mashhad

چکیده

Background and Aim : Although Helicobacter pylori (H. pylori) infection has been demonstrated to be associated with several gastrointestinal disorders, it is still not clear which patients’ lifestyle factors are associated with H. pylori infection in the Iranian population. This study aimed to investigate the relationship between H. pylori infection and patient with different lifestyle factors such as stress level and diet. Methods : In this study, two gastric biopsies were taken from ۱۳۴ patients with gastrointestinal symptoms who were referred to two endoscopy centers. The patients answered a questionnaire, including four items as follows: stress level, tea consumption, tobacco, fruits and raw vegetables. For confirming the presence of H. pylori DNA in a biopsy, the glmM gene was identified by PCR. A Chi-Squared test was used to evaluate the relationship between each factor and the prevalence of infection.Results : Among the ۱۳۴ samples, H. pylori was isolated from ۵۷ (۴۳%) patients including ۲۶ men and ۳۱ women. According to the statistical testing the P-value for stress level, tea consumption, tobacco and fruit and raw vegetable was detected < ۰.۵, < ۰.۷۵, < ۰.۵and < ۰.۵, respectively. Conclusion : There was no association between stress level, consumption of tea, tobacco and fruit and raw vegetable and H. pylori-positive status. The small population analysis of this study can affect the results.

کلیدواژه ها

Helicobacter pylori, Chi-squared, stress, endoscopy, glmM

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