The first case of fatal mucormycosis in a patient with Covid ۱۹ in Ghaem Hospital of Mashhad

  • سال انتشار: 1400
  • محل انتشار: بیست دومین کنگره میکروب شناسی ایران (مجازی)
  • کد COI اختصاصی: MEDISM22_308
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 220
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نویسندگان

Hossein Zarrinfar

Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Reza Basiri

Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Negin Hosseini

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

Mohammad Javad Najafzadeh

Department of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Khalil Talebi

Department of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Mohammadali Ghanbari

Department of Parasitology and Mycology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

چکیده

Background and Aim : Fungal infections are one of the most common infections, especially in susceptible and immunocompromised patients. In some cases, the concurrence of fungal infections such as mucormycosis with other infections such as COVID-۱۹ can disrupt the treatment and control of the infection.Methods : The patient was a ۷۰-year-old woman with underlying diabetes who was admitted to Ghaem Hospital in Mashhad due to COVID-۱۹. He had sinusitis at the beginning of hospitalization and the maxillary sinuses were rapidly expanding necrotic. The sinus tissue specimen was examined for routine mycological procedures.Results : The results of direct experiments are reported by observing broad mycelium without septate (non-septate hyphae), with a Rhizopus spp. colony. Despite timely treatment with amphotericin B and other supportive therapies during COVID-۱۹, the patient died after ۱۰ days due to disease progression.Conclusion : Mucormycosis is one of the deadly and acute infections that timely diagnosis and treatment with new antifungals can be effective in reducing mortality, especially among COVID-۱۹ patients.

کلیدواژه ها

Fungal infection, Mucormycosis, COVID-۱۹, Mashhad

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