Seroepidemiological Investigation of SARS-CoV-۲ Infection among Asymptomatic Children in Tehran
- سال انتشار: 1400
- محل انتشار: بیست دومین کنگره میکروب شناسی ایران (مجازی)
- کد COI اختصاصی: MEDISM22_301
- زبان مقاله: انگلیسی
- تعداد مشاهده: 235
نویسندگان
Department of Microbiology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran
Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Infectious Disease Epidemiology Unit of Healthcare-associated Infections, Surveillance of Antibiotic Resistance and Consumption Unit of Gastrointestinal Infections, Zoonoses and Tropical Infections Robert Koch Institute
Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran and Department of Epidemiology, School of Public Health, Iran University of Medical Science, Tehran, Iran
چکیده
Background and Aim : COVID-۱۹ is an emerging infectious disease; however, there is little data about the infection, disease severity and its relationship to demographic characteristics in children. In current study, a seroepidemiological survey was done to show infection rate among asymptomatic children in Tehran.Methods : In this investigation, children younger than ۱۴ years old who had referred to laboratories during invitation through Snapp urban transportation system, public health centers, and outpatients’ admission units of private and governmental clinics during autumn, winter, spring and summer entered to the study. Blood samples were collected in gel clotted tubes, and related sera were preserved for measurement of IgG antibody ratio against SARS-CoV-۲ using EUROIMMUN ELISA kit. Demographic information and infection status in participants were reported by completing questionnaires and the relationship between variables were examined by statistical analysis.Results : Out of ۱۱۴۲ blood samples collected from children with no common COVID-۱۹ symptoms, history of SARS-CoV-۲ infection was detected in ۳۳.۳% of them (۳۸۱/۱۱۴۲). Borderline status was characterized among ۳.۵% (۴۰/۱۱۴۲) of the samples. The infection rate was higher among children lower than six years old in compare to other age groups. Conclusion : Results of this study showed that SARS-CoV-۲ infection can occur in children, which could be without common symptoms. Restriction of children from contact with family members who are at increasing risk of the infection is recommended during the pandemic to reduce its secondary transmission.کلیدواژه ها
ELISA, COVID-۱۹, Immunoglobulin G, SARS-CoV-۲, Antibody ratioمقالات مرتبط جدید
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