Incidence, Characteristics, and Outcome of COVID-۱۹ in Patient on Liver Transplant Program: A Retrospective Study in North of Iran
- سال انتشار: 1400
- محل انتشار: بیست دومین کنگره میکروب شناسی ایران (مجازی)
- کد COI اختصاصی: MEDISM22_294
- زبان مقاله: انگلیسی
- تعداد مشاهده: 263
نویسندگان
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Mohammad Sadegh Esmaeili Delshad
Department of General Surgery, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
چکیده
Background and Aim : The risk of severe COVID-۱۹ disease seems to be higher in individuals with solid organ transplantation. Therefore, the purpose of the present study is to describe the laboratory data and epidemiologic factors of liver transplant recipients with diagnosed COVID in comparison with the patients waiting for liver transplantation.Methods : In this study, we evaluated the records of patients on the waiting list for liver transplantation and recipients of a liver transplant. Demographic data, underlying disease, history of drug use, and participants’ outcomes were collected. The diagnosis of SARS-CoV-۲ infection for all patients was confirmed using a nasopharyngeal swab specimen with real-time RT-PCR. During the study period, ۱۷۲ patients were enrolled, among whom ۸۵ patients (۴۹.۴%) were on the waiting list for liver transplantation and ۸۷ patients (۵۰.۶%) were recipients of a liver transplant.Results : Out of them, ۱۰ (۵.۸%) had a positive result for SARS-CoV-۲. Of these patients, ۶.۹% (۶/۸۷) and ۴.۷% (۴/۸۵) of patients on the waiting list and recipients of liver transplant were positive for SARS-CoV-۲, respectively. Patients on the waiting list with COVID-۱۹ infection had a higher median of albumin, ALT, AST, TBIL, DBIL, HDL, and LDL values compared to recipients of a liver transplant. In summary, the incidence of COVID-۱۹ in liver transplant patients was slightly high. Conclusion : The existence of underlying liver diseases should be well known as one of the poor predictive factors for worse outcomes in patients with COVID-۱۹. So, comparative studies are recommended to identify risk factors for COVID-۱۹ in patients with liver injury.کلیدواژه ها
SARS-CoV-۲, COVID-۱۹, Liver transplant patients, Iranمقالات مرتبط جدید
اطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.