Antimicrobial effect of nanocarbons synthesis from glucose and starch on a number of food-borne pathogens
- سال انتشار: 1400
- محل انتشار: بیست دومین کنگره میکروب شناسی ایران (مجازی)
- کد COI اختصاصی: MEDISM22_246
- زبان مقاله: انگلیسی
- تعداد مشاهده: 304
نویسندگان
Department of Food Science and Technology, Urmia University, Urmia, Iran; CEO of Nobonyad Nasr Food Industry Specialists Company, Tehran, Iran
Department of of Food Hygiene, Department of Internal Medicine, Urmia University, Urmia, Iran
Department of of Food Hygiene, Department of Internal Medicine, Urmia University, Urmia, Iran
چکیده
Background and Aim : With increase of microbial resistance to antibiotics, many efforts have been made to find strong, low-resistance, low-cost antimicrobials to replace these compounds. Simultaneously with the advent of nanotechnology in medical science, researchers have tried to produce metal nanoparticles to produce antibiotics that, in addition to solving the problems of chemical antibiotics, have better effects on pathogenic microorganisms. However, due to the high cytotoxicity of metal nanoparticles, the production of green nanoparticles became one of the important issues in this field. Nanocarbons synthesized from organic compounds such as glucose and starch can be considered as a suitable alternative in this field due to their bactericidal and bacteriostatic properties and lack of cytotoxicity. Methods : In this study, organic compounds such as glucose and starch were used to produce nanocarbons. Nanocarbon synthesis was performed by hydrothermal method (۱۴۰ ° C for ۶ hours). Also, to evaluate the antimicrobial effect of synthesized nanocarbons, by Well diffusion method from concentration of ۰.۲ molar glucose and starch against L. monocytogenes (ATCC ۱۹۱۱۵), Salmonella typhimurium (ATCC ۱۴۰۲۸) and Staphylococcus aureus (ATCC ۲۵۹۲۳) used. Results : The results showed that nanoparticles synthesized from glucose and starch had a good antimicrobial effect on all pathogenic bacteria. So that the highest mean diameter of inhibitory at ۰.۲ M glucose was on Listeria monocytogenes, Staphylococcus aureus and Salmonella typhimurium with mean diameters of ۱۴.۳۶, ۱۴ and ۱۱.۷۳ mm, respectively. Also, the inhibitory effect of glucose-synthesized nanocarbons were greater than starch-synthesized nanocarbons and the lowest level of inhibition was observed on Salmonella typhimurium. Conclusion : The results of the present study showed that synthetic nanocarbons from organic compounds have strong antibacterial effects against all pathogenic bacteria. Therefore, due to the increasing antibiotic resistance of some pathogens as well as problems caused by metal nanoparticles such as cytotoxicity, so these synthesized nanocarbons can be a suitable alternative for different uses in medicine and the food industry.کلیدواژه ها
Nanocarbon, Glucose, Starch, Cytotoxicity, Antimicrobialمقالات مرتبط جدید
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