Determination of Antimicrobial Resistance Pattern among clinical isolates of Escherichia coli collected Bagheralolulom hospital in Ahar

Background and Aim : Escherichia coli (E. coli) are a group of gram-negative bacteria that normally reside in the intestine of healthy people, but some strains can cause infection in the digestive tract, urinary tract, or many other parts of the body. Antibiotics are used to treat infections caused by this bacterium. Unfortunately, antibiotic resistance has become an increasingly critical problem in many countries like Iran. Since there are very few published data on antibiotics resistance in Ahar, the aim of this study was to survey the pattern of antimicrobial resistance among clinical isolates of Escherichia coli collected Bagheralolulom hospital in Ahar Methods : This cross-sectional descriptive study was performed on ۱۰۰ clinical Escherichia coli strains collected from Ahar s Bagherololum hospital. The selective culture media and biochemical test were used for the identification of Escherichia coli isolates. Antimicrobial susceptibility test was performed using Kirby-Bauer disk diffusion method against common antibiotics. Results : Isolates showed the highest resistance to amoxicillin (۹۷%), whereas gentamaycin was the most effective drug, with only ۸.۴% resistance. The frequency of multi drug resistance (MDR) to more than ۵ antibiotics was ۷۹%.Conclusion : As the results of this study indicate, multidrug resistance is an increasing therapeutic concern and treatment requires further attention to the results of susceptibility tests. Antibiogram is recommended before starting antimicrobial treatment.

کلیدواژه ها:

Antimicrobial Resistance Pattern ، Escherichia coli ، antibiogram