Investigating the safety of carbon nanotubes for tissue engineering applications

Carbon nanotubes (CNTs) are one of the more exciting and debated class of materials of the past decades. Since their discovery, more than ۲۰ years ago that has the potential for successful engineering of tissue. CNTs are tubes made of carbon. Carbon nanotubes include single wall and multi wall with diameters typically measured in nanometers. CNTs and graphene oxidenano sheets are mainly used in tissue engineering as structural and functional components in scaffolds that bring biomimetic advantages. Many researches have evaluated influence of CNTs on organs or tissues It seems that the development of CNTs with almost no hazard to human health is possible, because recent studies suggest that CNT toxicity, agglomeration, and in vivo clearance are directly related to specific features of this material, such as their dimensions (length, thickness, rigidity). CNTs offer superior mechanical and electrical properties. Therefore, may be used to improve the mechanical and electrical properties of biodegradable scaffolds for bone, neural and cardiac tissue engineeringapplications. Conclusively, this review provides new insight into safety of CNTs and the remarkable potential of CNT aligned scaffolds in improving the functionality of engineered tissue that signifies their feasibility in tissue regenerative medicines and stem cell therapy.

کلیدواژه ها:

Tissue engineering ، Carbon nanotubes ، Safety ، Scaffold