Bleeding Diathesis or Prothrombotic State, Which One Predict the COVID-۱۹ Prognosis in Pregnancy?
- سال انتشار: 1400
- محل انتشار: فصلنامه زنان و مامایی و سرطانهای زنان، دوره: 6، شماره: 4
- کد COI اختصاصی: JR_JOGCR-6-4_011
- زبان مقاله: انگلیسی
- تعداد مشاهده: 306
نویسندگان
Department of Obstetrics and Gynecology, Faculty of , University of , , Iran
Department of Obstetrics and Gynecology, Faculty of , University of , , Iran
Department of Obstetrics and Gynecology, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده
Background & Objective: Since the first reported respiratory distress syndrome due to the new version of the coronaviruses family, COVID-۱۹, there is a concern about the possible maternal and perinatal outcome of new infection in a short and even long time, our information about the prognosis of pregnancy in sync with COVID-۱۹ is limited. What is our task as scientists in eliminating the unknown facts? Materials & Methods: Here we try to present a couple of pregnant cases in their third trimesters of pregnancy that complicated with two contrary complication of COVID-۱۹ infection, intending to illuminate the best management strategy in COVID-۱۹ infected pregnant. Results: The first case had experienced thromboembolism, and also bleeding accident, who fortunately survived unlike the other case, who expired due to multi-organ failure and impossibility of anticoagulant agent administration for the suspected pulmonary thromboembolic accident. Conclusion: The prior report revealed the thrombo-inflammatory and hypoxic effect of COVID-۱۹ that could lead to microvascular thrombosis and progression, which enforce health care providers, introducing the anticoagulant agents to decline COVID-۱۹ mortality, especially in a critically ill patient. Pregnancy is associated with coagulation abnormality which could intensify the COVID-۱۹-induced coagulopathy. But, one should balance the harm and benefit of such a hazard approach, is there any concern about vascular damage of COVID-۱۹ and subsequent bleeding, that could be exacerbated with high dose anticoagulant agent administration? The other question that we want to discuss in the present report is about comparing the cost and benefit of anticoagulant therapy?کلیدواژه ها
Bleeding, COVID-۱۹, Maternal outcome, Morbidity, Perinatal outcome, Pregnancy, Thromboembolismاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.