Efficiency of Dimethicone and Symbiotic Approaches in Infantile Colic Management

  • سال انتشار: 1400
  • محل انتشار: مجله علمی ناباروری ایران، دوره: 12، شماره: 3
  • کد COI اختصاصی: JR_IRJN-12-3_005
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 196
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نویسندگان

Behzad Barekatian

Department of Pediatrics, Division of Neonatology, Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Roya Kelishadi

Department of Pediatrics, School of Medicine, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran

Farinaz Sohrabi

Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran

Maryam Yazdi

Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran

چکیده

Background: Infantile colic (IC) (a frequent reason for infantile referral to pediatricians) is a common indiscoverable problem posing concerns for parents. Varieties of theories for the etiology of IC have been raised, and different therapeutic approaches have been recommended in this regard. This study aimed to assess and compare the efficiency of dimethicone versus symbiotic in the treatment of IC. Methods: This randomized clinical trial was conducted on ۱۴۹ infants with the diagnosis of IC based on the Wessel criteria from ۲۰۱۷ to ۲۰۱۸. The study population was randomly divided into two groups of Dimethicone (n=۷۳) (five drops of dimethicone, three times a day for three weeks) and Symbiotic (n=۷۶) (five daily drops of symbiotic for three weeks). Utilized symbiotic contained fructooligosacharide periodic and probiotic of ۱۰۹CFU of Bifidobacterium lactis. Duration of an infant crying per day, numbers of crying per day, sleep duration per day, and number of defecation per day were obtained prior to the study and at the end of each week. Results: There was no statistically significant difference between the groups regarding age, gender, and values of breastfeeding (P> ۰.۰۵). Crying duration, numbers of crying, and sleep duration per day improved significantly in the dimethicone group (P< ۰.۰۵) within the time as the symbiotic-treated group (P< ۰.۰۵); however, the comparison of the two groups for IC treatment revealed no statistical differences (P> ۰.۰۵). Conclusion: The findings of the current study presented that dimethicone and symbiotic could successfully improve IC symptoms regarding crying times, as well as the duration and sleeping time per day. Comparison of these two remedies for IC treatment revealed no significant differences.    

کلیدواژه ها

Dimethicone, Infantile colic, Symbiotic

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