The Global Prevalence and Distribution of Chlamydia pneumoniae, Helicobacter pylori, Cytomegalovirus and Herpes simplex virus in Patients with Coronary Artery Disease in Molecular and Serological Studies; A Systematic Review and Meta-analysis
محل انتشار: بیست و یکمین کنگره بین المللی میکروب شناسی ایران
سال انتشار: 1399
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 277
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شناسه ملی سند علمی:
MEDISM21_348
تاریخ نمایه سازی: 23 مرداد 1400
چکیده مقاله:
Background and Aim : Coronary Artery Disease (CAD) is one of the most important causes of death worldwide. The aim of this study was to determine the prevalence of C. pneumoniae, H. pylori, Cytomegalovirus (CMV) and Herpes simplex virus (HSV) in CAD patients based on published serological and molecular studies.Methods : A systematic literature search was conducted in Medline (via PubMed), Embase, Scopus and Web of Science databases (۱۹۹۶-۲۰۱۹). Both molecular and serological studies were analyzed using STATA software (Version ۱۴).Results : ۱۴۵ studies were included for final analysis. We gathered and investigated the prevalence of C. pneumoniae (۲۵.۱% [۹۵% confidence interval (CI) ۲۱.۵-۲۸.۸%]), H. pylori (۱۲.۸% [(۹۵% CI) ۴.۰-۲۲.۰%]), CMV (۶۴.۴% [(۹۵% CI) ۵۷.۷-۷۳.۰%]) and HSV (۳۱.۸% [(۹۵% CI) ۲۱.۵-۴۲.۲%]) in CAD patients from the analysis of molecular studies. Additionally, in serological studies, the prevalence of mentioned pathogens were ۷۲.۷% [(۹۵% CI) ۶۷.۸-۷۷.۶%], ۶۳.۳% [(۹۵% CI) ۶۰.۰-۶۶.۵%], ۶۲.۲% [(۹۵% CI) ۵۸.۰-۶۶.۳%] and ۳۴.۳% [(۹۵% CI) ۲۳.۶-۴۵.۱%] respectively.Conclusion : Interestingly, there was only a significant increase in the prevalence of C. pneumoniae and H. pylori in serological studies compared to the reported data from molecular studies, while the prevalence of CMV and HSV were the same in both types of studies.
کلیدواژه ها:
نویسندگان
Parastoo Sharifian
Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
Nooshin Nazari Nejad
Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
Ayda Vahabi
Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
Somayeh Yaslianifard
Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran