Study on correlation between demodex folliculorum density and androgenic alopecia
- سال انتشار: 1399
- محل انتشار: بیست و یکمین کنگره بین المللی میکروب شناسی ایران
- کد COI اختصاصی: MEDISM21_333
- زبان مقاله: انگلیسی
- تعداد مشاهده: 272
نویسندگان
Dermatologist, Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
BSC of Microbiology, R&D Department, Luvencare Company, Tehran, Iran
PhD of Microbiology, R&D Department, Luvencare Company, Tehran, Iran
BSC of Microbiology, R&D Department, Luvencare Company, Tehran, Iran
چکیده
Background and Aim : Demodex folliculorum is an obligate parasite of the human hair follicles. D. folliculorum can mechanically block follicles. Androgenetic alopecia (AGA) is a kind of hair loss that affected by testosterone hormone. Inflammatory activators such as Demodex infestation may play a role in the pathogenesis of some cases of androgenetic alopecia. The goal of this study is to assess the relationship between Demodex density and AGA.Methods : The study comprised ۱۰۰ patients with AGA and ۱۰۰ controls without alopecia symptoms. We take sebum smear from hairless areas, examined under a microscope, and counted Demodex mites/cm۲. Based on references positive Demodex test means five or more mites/cm۲.Results : In our study, positive Demodex tests were seen in ۳۶ patients with AGA (۳۶%) and in ۴ controls (۴%). Among ۳۶ patients with positive test, ۲۸ cases of them were women (۳۴.۵%) and ۸ cases of them were men (۴۲.۱%). The average of Demodex density in AGA cases was ۳.۸۵ mites/cm۲Conclusion : There are some mechanisms that seem intensify hair loss by Demodex. The Demodex use the chelicerae to cut the epithelial cells of the host skin, feeding nutrients and bacteria from the hair roots. Demodex may be one of second factor (co factor) in hair loss and one of main factor in resistant to cure alopecia and the other disorder that lead to hairless.کلیدواژه ها
Androgenetic alopecia, Demodex folliculorum, Hair lessاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.