Study of the effect of the wound dressing Polyvinyl alcohol nanofiber containing Eucalyptus globules extract on surgical wounds infected by staphylococcus aureus in a rat model
- سال انتشار: 1399
- محل انتشار: بیست و یکمین کنگره بین المللی میکروب شناسی ایران
- کد COI اختصاصی: MEDISM21_250
- زبان مقاله: انگلیسی
- تعداد مشاهده: 290
نویسندگان
Department of Clinical Science, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran
Department of Clinical Science, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran
Department of Clinical Science, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran
Faculty of Materials and Metallurgical Engineering, Semnan University, Semnan, Iran
Department of Clinical Science, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran
چکیده
Background and Aim : : Wound infection is one of the frequent complications in patients with a surgical operation. The use of nanotherapeutic agents engineered within the nanoscale is one of the most promising strategies for overcoming the wound infection. This study aimed to investigate the effect of the wound dressing Polyvinyl alcohol(PVA) nano fiber-containing Eucalyptus globules against Staphyloccocus. areous in surgical wounds using a rat model.Methods : ۶۰ male Wistar rats were randomly divided into four groups of treatment by extract+PVA, PVA, Nitroforazon, and Normal saline. A circular incision was made on the dorsal inter-scapular region of each rat. Then rats were inoculated with ۱۰^۶ CFU of S. areous at the site of skin wound. Treatments and normal saline ( control) were applied once every two days during the experiment. Tissue specimens were weighted and homogenized in broth on days ۷ and ۱۴. colony counts were conducted after serial dilution preparation.Results : a load of bacteria in untreated and treated by extract+PVA groups on day ۷ were ۸.۳*۱۰^۷ and ۴*۱۰^۶ and on day ۱۴ were ۵.۳۷*۱۰^۶ and ۶.۷۲*۱۰^۵ respectively while in Nitroforazone group was ۲.۸*۱۰^۶ and ۳.۸۵*۱۰^۵ CFU/ml.Conclusion : the results of this study showed the wound dressing Polyvinyl alcohol nanofiber containing Eucalyptus globules extract on surgical wounds infected by staphylococcus aureus has an antimicrobial effect similar to standard treatment with traditional antibiotics. Therefore nanotherapeutic agents consider as a potential alternative instead of antibiotics.کلیدواژه ها
wound infection, Nanoextract, Eucalyptus globulesمقالات مرتبط جدید
- The Effect Of Stroke Following Stress On Malondialdehyde Levels
- The Effect Of Eight Weeks Of Moderate-Intensity Interval Training With Cumin Extract On The Levels Of Lipocalin-۲, Interleukin-۱ Beta And Body Composition Of Obese Women With Hypertension
- Investigating The Influence Of Nurse-Led Support Programs On Rehabilitation And Physical Activity In Stroke Patients: A Systematic Review And Meta-Analysis
- معنویت و سلامت در پرستاری (یک مطالعه مروری)
- بررسی روش های تشخیص وپیشگیری از بیماری های التهابی روده
اطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.