Mycoplasma hominis Bacterial Role in infertile women

Background and Aim : Infertility is one of the most important problems for every family especially for women. The aim of this study is to test the prevalence of M. hominis, in infertile women. The patients that arrive to infertility clinics (Royan Institute in Tehran) with the cervical smear culture analysis request are asked to fill in a questionnaire about infertility smear collection.Methods : In this case control study presence of M. hominis were analyzed in tested women who have been sent by gynecologists because of infertility. In this study we have compared ۴۰ infertile females with unexplained infertility and ۴۰ Normal pregnant women as a control case group. The samples were sent to microbiology laboratory. The information were analyzed with S.P.S.S software by frequency, chi-square, Mann-Whitney & T-test Method.Results : The average age in patients and control groups were ۲۸.۹۲±۶.۲۰ and ۲۴.۹۷±۴۳.۳۷ the value of M.hominis. In infertile cases were ۸. (۲۰%) and in Normal pregnant were ۳(۷.۵%) ( x= ۲.۵۸) and (P= ۰.۱) then we have not found statistically significant differences in the M.hominis frequency of the patients. But we have found statistically significant relations between educational levels, the history of abdominal pains, the history of genital secretions and infertility, also we have not found statistically significant relations between marriage age, history of genital infections, history of smoking and infertility.Conclusion : We have shown a significantly M. hominis infections increase in the infertile women. The similarities between this study and the results obtained by others are limited and it may be due to different cultural and normal values in various societies. Though statistically non-significant due to limited number of subjects. However the difference observed in the prevalence infection between cases and controls indicates an association between M. hominis infection and infertility. So, it is suggested to check up those patient with unexplained infertility, for genital micro-organisms infections, and if positive, to control the rate of infertility with a suitable and cost effective therapy.