Antibacterial resistance of Acinetobacter baumannii isolated from Mostafa Khomeini Hospital to selected antibiotics

Background and Aim : Acinetobacter baumannii is an opportunistic pathogen, related with nosocomial infections such as bacteremia, urinary tract infections (UTIs), and ventilator associated pneumonia. A. baumannii strains are first line cause of infection, especially in patients hospitalized at intensive care units (ICUs). The aim of the current study was the evaluation of pattern of antibacterial resistance of A. baumannii isolates .Methods : This study was performed on ۷۲ A. baumannii isolates collected from Mostafa Khomeini Hospital in Tehran,Iran. The antibiotic susceptibility pattern was examined using Kirby-Bauer disk diffusion susceptibility test.Results : According to the antibiogram test, among the ۷۲ isolates from patients admitted to the ICU, the pattern of antibiotic resistance were respectively: cefipime (۹۷.۲%), ceftriaxone (۹۵.۸%), amikacin (۹۴.۴%), imipenem (۸۰%), pipracilin-tazobactam (۷۱.۴%), meropenem (۶۸.۶%), gentamicin (۶۲.۸%), tobramycin (۵۷.۱%) and tetracycline (۴۸.۶%).Conclusion : our results show that antimicrobial resistance of A. baumannii in Iran has increased. according to the findings, novel prevention and treatment strategies against A. baumannii infections are necessary. Furthermore, these data may assist in revising and updating treatment guidelines in hospitals to reduce the emergence of antimicrobial resistance.

کلیدواژه ها:

Acinetobacter baumannii ، antibacterial resistance ، nosocomial infections