Antimicrobial Stewardship in the Treatment of Asymptomatic Bacteriuria (ASB)

سال انتشار: 1399
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 233

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شناسه ملی سند علمی:

MEDISM21_101

تاریخ نمایه سازی: 23 مرداد 1400

چکیده مقاله:

Background and Aim : Unnecessary antibiotic treatment is associated with acquisition of drug-resistant pathogens, Clostridium difficile infection, and other drug-related adverse events. Antimicrobial stewardship designed to promote the optimal use of antimicrobial agents, including their choice, dosing, route, and duration of administration. The primary goal of antimicrobial stewardship is to optimize clinical outcomes while minimizing unintended consequences of antimicrobial use. Additional benefits include reducing antimicrobial resistance. Asymptomatic bacteriuria (ASB) is the presence of ۱ or more species of bacteria growing in the urine at specified quantitative counts, irrespective of the presence of pyuria, in the absence of signs or symptoms attributable to urinary tract infection (UTI).Methods : The present study on Antimicrobial stewardship programs have identified the treatment of ASB as an important contributor to inappropriate antimicrobial use, which promotes resistance. Guidelines from the Infectious Diseases Society of America recommend treating ASB only in pregnant women or immediately prior to a urologic procedure likely to involve mucosal injury.Results : Clinical distinction between UTI and ASB in some populations with a high prevalence of bacteriuria is difficult. Obtaining urine cultures when not clinically indicated, including for routine screening, promotes inappropriate antimicrobial use. Laboratory evidence of pyuria and bacteriuria is necessary for the diagnosis of ASB in patients without symptoms which benefit from antibiotic treatment.Conclusion : Educational interventions are effective ways to reduce rates of inappropriate ordering of urine cultures and the treatment of ASB.

نویسندگان

Narges Nooritalab

Social Security organization, Reference Laboratory