Effect Of Turmeric Ethanolic Extract On Group A Streptococcus β Hemolyticus

Background and Aim : Mohammad ebrahim Goli mehdi abadi* Introduction : Pharyngitis is one of the most common infection that general practitioners handled. It is estimated in one year there are ۱۵ million people with pharyngitis will come to the doctor. American Society of Microbiology said that ۹۴,۳ % from ۴۰۲ patient who were suspected pharyngitis received antibiotic therapy even without indication of antibiotic therapy. Antibiotic resistance is becoming a great threat for the world today. Turmeric domestica is a plant that is widely used in all over the world and some research said that it has anti -inflammatory, antioxidant, and antimicrobial effect. Aim: The aim of this study is to find the antibacterial effect of Turmeric (curcuma) domestica ethanolic extract on Group A Streptococcus β hemolyticus and find the Minimum Bactericidal Concentration (MBC) value.Methods : This was in vitro experimental study with broth microdilution method and inoculation on agar blood media to find the MBC. Treatment group consisting of, media (Mueller Hinton Blood Broth), Group A Streptococcus β hemolyticus bacteria, and ۵ concentrations (۳۱۲.۵ μg/ml, ۶۲۵ μg/ml, ۱۲۵۰ μg/ml, ۲۵۰۰ μg/ml, ۵۰۰۰ μg/ml) of Turmeric(Curcuma) domestica extract.Results : There is no bacterial growth at ۵۰۰۰ ?g/ml concentration on solid media, but there are less bacterial growth at ۲۵۰۰ ?g/ml than at concentration ۳۱۲.۵ ?g/ml, ۶۲۵ ?g/ml, ۱۲۵۰?g/ml.Conclusion : There is an antibacterial effect of Turmeric(Curcuma) domestica ethanolic extract on Group A Streptococcus β hemolyticus with MBC value in range ۲۵۰۰ – ۵۰۰۰ μg/ml.

کلیدواژه ها:

Group A Streptococcus β hemolyticus ، MBC ، Turmeric