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Malignant phyllodes Tumor of the Breast; Presentation of an Uncommon Case and Review of the Literature

عنوان مقاله: Malignant phyllodes Tumor of the Breast; Presentation of an Uncommon Case and Review of the Literature
شناسه ملی مقاله: JR_ARCHB-7-2_002
منتشر شده در شماره 2 دوره 7 فصل May در سال 1399
مشخصات نویسندگان مقاله:

Sumaiya Iqbal - Department of Obstetrics and Gynecology, Latifa Women and Children's Hospital, Dubai, UAE
Juwairiyan Iqbal - Medical Education, Dubai Medical University, Dubai, UAE
Nowfala Nowshad - Department of Obstetrics and Gynecology, Latifa Women and Children's Hospital, Dubai, UAE
Khadeeje Mohammad - Department of Obstetrics and Gynecology, Latifa Women and Children's Hospital, Dubai, UAE

خلاصه مقاله:
Background: Phyllodes tumours are rare fibroepithelial neoplasm ofconnective tissue of the breast accounting for ۰.۳-۱% of all breast tumours with۱۰% of them being malignant. They resemble fibroadenomas clinically and can bemistakenly ignored.Case presentation: A ۳۸-year-old unmarried Philipino lady presented to theprimary health center with a mass in the right breast for the past year. Over thepreceding ۶ months, it had progressively increased in size and pain. Onexamination, a ۵ x ۳ cm firm and lobulated mass was palpated in the right upperouter quadrant. Ultrasound scan showed a solid ۴.۲۵ x ۳.۳ x ۲.۴ cm mass withheterogeneous mixed echopattern. She was referred to Surgery department wherean ultrasound-guided core biopsy showed a lesion suspicious for benign phyllodestumor. An excision biopsy revealed three foci of malignant Phyllodes on thebackground of fibroadenoma. A staging CT was performed which showed noevidence of lymph node involvement or distant metastasis. A simple mastectomywas performed and histopathology confirmed the diagnosis of malignantphyllodes tumor. Postoperatively, the patient is on regular follow up in the breastclinic and physiotherapy department. Conclusion: Phyllodes tumor bears specific clinical characteristics and shouldbe considered as a differential diagnosis in any mass lesion of the breast..Diagnosis and management are crucial in phyllodes tumor because of theirmalignant potential recurrence. Clinicians should be competent in distinguishingbetween fibroadenoma and a phyllodes tumor. Lastly, given the rarity of phyllodestumors, there is a need to establish guidelines to incorporate regular follow up forearly detection of distant metastasis.

کلمات کلیدی:
Breast cancer, phyllodes tumor, malignancies

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1231110/