Comparison of CPP-ACP, Fluoride Varnish and Gel effects on enamel microhardness of permanent teeth: In-Vitro

  • سال انتشار: 1400
  • محل انتشار: مجله بین المللی کودکان، دوره: 9، شماره: 6
  • کد COI اختصاصی: JR_INJPM-9-6_024
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 327
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نویسندگان

Bahram Akbari

Dentistry Student, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.

Haleh Hali

Assistant Professor, Pediatrics Department, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.

Abbas Mesgarani

Associate Professor, Endodontics Department, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.

Mahmood Moosazadeh

Assistant Professor, Research Center for Health Sciences, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.

چکیده

Background Dental caries occurs due to the imbalance in the course of demineralization-remineralization in favor of demineralization. With remineralization, some signs of halted progression could be observed in the primary stages. The aim of this study is to in-vitro investigation of the effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP), fluoride varnish, and fluoride gel on the microhardness of the enamel of permanent teeth. Materials and Methods: In this in vitro study, ۳۴۴ specimens prepared from human premolars were randomly divided into four groups (n=۸۶ specimens in each group). After preparing the specimens, the initial enamel value was first evaluated by Vickers microhardness technique. The specimens were immersed in a demineralizing solution and then treated with remineralizing compounds (I. Control, II. Fluoride varnish, III. Fluoride gel and IV. CPP-ACP). Microhardness values were re-measured at the end of demineralization and remineralization stages. The data were analyzed using SPSS software (version ۱۶.۰). Results: The results of the present study indicated a statistically significant difference in all groups in terms of initial enamel microhardness (۰.۲۸۸ ± ۴۲.۷۷), remineralization (۰.۲۱۳ ± ۲۶.۸۹), and demineralization values (۰.۱۶۷ ± ۶۳.۸۷) (p < ۰.۰۰۱). Besides, there was a statistically significant difference in different groups in terms of remineralization values (p < ۰.۰۰۱). In other words, the mean microhardness was ۲۴۱.۲۱ ±۱۵.۶۰ in Group III, ۲۲۱.۱۲ ± ۷۵.۶۹ in Group II, ۲۱۱.۱۶ ± ۴۳.۰۴ in Group IV, and ۱۷۸.۲۱ ± ۶۳.۹ in group- I. Conclusion All remineralizing compounds resulted in enhanced microhardness of the enamel. Nevertheless, the fluoride-containing products showed greater potential in improving the level of microhardness and strength of the teeth compared to the compounds containing CPP-ACP.

کلیدواژه ها

CPP-ACP, Fluoride, microhardness, tooth enamel, Remineralization

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