Investigation of sources and production methods of bioactive peptides effective on human health: A systematic review
- سال انتشار: 1399
- محل انتشار: مجله بهداشت و توسعه، دوره: 9، شماره: 1
- کد COI اختصاصی: JR_JHD-9-1_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 249
نویسندگان
چکیده
Background: The value of proteins in human health as the main source of amino acids has been proven. In addition to nutritional value, proteins also have biological functions that are expressed by bioactive peptides. Production methods of bioactive peptides affect their function. This article aims to investigate sources and production methods of bioactive peptides effective on human health. Methods: For gathering information in this review, English articles between ۱۹۸۸ and ۲۰۱۸ containing one of the keywords "bioactive peptides, enzymatic hydrolysis, anti-cancer and anti-hypertensive agents" were searched in PubMed, Scopus, Science Direct and the Islamic World Science Citation Database (ISC). Among ۶۴۳ papers found, ۲۸ articles related to the subject were selected. Results: The articles show that utilizing the enzymatic hydrolysis method for therapeutic applications causes them to be more stable in comparison with fermentation and solvent extraction methods and is safer than the other two methods. Also, the positive health effects of these compounds include reducing the risk of chronic diseases, increasing immune function, reducing cholesterol, antimicrobial activity, as well as antioxidant, anti-clotting, antihypertensive, and anticancer properties. Conclusion: In recent years, the role of bioactive peptides as therapeutic compounds has been highlighted. Bioactive peptides can play an effective role in human health. Therefore, investment and planning in this area can affect the future health of the country.کلیدواژه ها
Human health, Bioactive Peptides, Enzymatic Hydrolysis, Anticancer, Antihypertensiveاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.