Cytotoxicity and genotoxicity of nanoparticles and drug nancariers
سال انتشار: 1399
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 194
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شناسه ملی سند علمی:
CIGS16_061
تاریخ نمایه سازی: 14 اردیبهشت 1400
چکیده مقاله:
The nanotechnology has been an emerging field with exceptional potentials in biological applications including drug delivery systems as well as nanodevices. With all these applications, the safety of nanoparticles is a matter of debate and it is being intensively investigated. The cytotoxicity and the genotoxicity of nanoparticles are the major area of interest in these research. Furthermore, various structure of nanoparticles as well as their coating and decorations have used as nanocarriers for drug delivery. Therefore, the toxicity and the safety of these nanocariers are the major concern in novel drug therapy. We will discuss the diversity of toxic responses with regards to cytotoxicity and genotoxicity in various cells.
نویسندگان
Mohammad H Ghahremani
Department of Toxicology-Pharmacology, Faculty of Pharmacy and Nanotechnology Research Center, Tehran University of Medical Sciences, Iran
Mohammad R Sepand,
Department of Toxicology-Pharmacology, Faculty of Pharmacy and Nanotechnology Research Center, Tehran University of Medical Sciences, Iran
Amir Shadboorestan
Department of Toxicology-Pharmacology, Faculty of Pharmacy and Nanotechnology Research Center, Tehran University of Medical Sciences, Iran