Evaluation of Antifungal Activity of Medicinal Plant Extracts on Candida albicans

  • سال انتشار: 1399
  • محل انتشار: فصلنامه زنان و مامایی و سرطانهای زنان، دوره: 6، شماره: 2
  • کد COI اختصاصی: JR_JOGCR-6-2_001
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 267
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نویسندگان

Mohamad Kazem Momeni

zabol universityAssistant Professor of Internal Medicine, Zahedan University of Medicine, Zahedan, Iran

Omid Bameri

Assistant Professor of Emergency Medicine, Department of Emergency Medicine, School of Medicine, Amir al momenin Hospital, Zabol university of medical sciences, Zabol, Iran

Mehrangiz Ghafari

zabol universityAssistant Professor of Pathology, Department of Pathology, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran

Sima Saravani

Department of Pharmacology, Zabol University of Medical Sciences, Zabol, Iran

Fereshteh Javadian

Zabol University of Medical Sciences, Zabol, Iran

چکیده

Today, opportunistic fungi, especially Candida albicans, are among the most common risk factors in patients with weakened immune systems. Fungal infections caused by Candida species and increasing number of azole-resistant strains are of great importance in immunocompromised patients. The toxicity of the drugs used, the development of resistance to these fungi, and the problems caused by drug interactions necessitate the use of more effective drugs with less toxicity. This study aimed to evaluate the antifungal activity of medicinal plant extracts on C. albicans. In this review study, Scopus, PubMed, MEDLINE, Google Scholar, SID, and Magiran databases were searched between ۲۰۰۰ and ۲۰۱۹ to identify related articles. The search keywords were “Candida albicans”, “Complementary”, “Herbal medicine” and their Persian equivalents. All in vivo and in vitro trials were included in the study. The reviewed studies showed the effectiveness of some compounds in inhibiting the growth of C. albicans. The results of the present research were in in-vitro conditions, but they need to be conducted in-vivo for human use.

کلیدواژه ها

Candida albicans, Plant extract, Antifungal activity

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