Is There an Association between Fetal Distress and Autism Spectrum Disorders (ASD) among Children? A Systematic Review and Meta-Analysis

  • سال انتشار: 1400
  • محل انتشار: مجله بین المللی کودکان، دوره: 9، شماره: 4
  • کد COI اختصاصی: JR_INJPM-9-4_002
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 438
دانلود فایل این مقاله

نویسندگان

Ensiyeh Jenabi

Autism Spectrum Disorders Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Erfan Ayubi

Department of Community Medicine, Zahedan University of Medical Sciences, Zahedan, Iran AND Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.

Mahsa Naemi

Assistant Professor, Department of Obstetrics and Gynecology, Shariati hospital, Tehran University of Medical Sciences, Tehran, Iran.

چکیده

Background Evidence regarding the relation between fetal distress and development of autism spectrum disorders (ASD) among children is rare. Therefore, this systematic review and systematic review and meta-analysis was conducted to assess the relation between fetal distress and ASD among children with stronger evidence. Materials and Methods: In this systematic review and meta-analysis, Medline, Scopus, Web of Science and Google Scholar were searched using the relevant keywords on observational studies from inception to October ۲۰۲۰ without any language restriction by two independent authors. The pooled odds ratios (OR), and ۹۵% confidence intervals (CI (were calculated from eligible studies used as random effect estimates of association among included studies. The inconsistency across results of studies was quantified using I۲ statistic. Data were analyzed using Stata software version ۱۳.۰. Results: From ۳۴۱ identified studies, eight studies (۶۸۴,۲۶۲ individuals) were included in the meta- analysis. The pooled estimates of OR did not show a significant association between fetal distress and the risk of ASD among children, respectively (OR = ۱.۲۷, ۹۵% CI = ۰.۸۸ to ۱.۶۷). There was medium heterogeneity among included studies (I۲=۵۰.۴%, P=۰.۰۴۹). Conclusion Our findings showed that fetal distress was not a risk factor for ASD among children. In a comparison to the previous meta-analysis, this study provides the most up-to-date evidence supporting a lack of significant association between fetal distress and ASD. Here, the association between fetal distress and ASD is still under discussion so that, further researches and umbrella reviews are needed.

کلیدواژه ها

Autism spectrum disorder, Children, Fetal distress, Systematic review

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.