The Characteristics and Outcomes of Patients Treated with Percutaneous Nephrolithotomy According to the Preoperative Renal Function Levels
- سال انتشار: 1399
- محل انتشار: فصلنامه تحقیقات بین رشته ای در اورولوژی، دوره: 2، شماره: 1
- کد COI اختصاصی: JR_TUMS-2-1_002
- زبان مقاله: انگلیسی
- تعداد مشاهده: 243
نویسندگان
Department of Urology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Department of Urology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Department of Urology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Hematology-Oncology and Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
چکیده
IntroductionThe principles of nephrolithiasis therapy in patients with chronic kidney disease are the same as in patients with normal kidneys. Percutaneous nephrolithotomy (PNL) is the standard treatment for patients with complex or large-volume upper urinary tract calculi. We reported the characteristics and outcomes of patients following percutaneous nephrolithotomy according to their preoperative renal function levels.MethodsIn this prospective cohort study, data on 53 consecutive patients treated with percutaneous nephrolithotomy in 6 months were collected. Patients were divided into 3 groups by estimated glomerular filtration rate (eGFR) including chronic kidney disease (CKD) stages 0, 1 and 2 (eGFR ≥ 60 mL/min/1.73 m2), stage 3 (eGFR = 30 to 59 mL/min/1.73 m2) and stages 4 and 5 (eGFR < 30 mL/min/1.73 m2).Results31 patients with CKD stages 0, 1 and 2, 17 patients with CKD stage 3, and 5 patients with stages 4 and 5 were followed up for at least three months. The mean eGFR before and after PNL was 80.1 vs. 85.9, 47.6 vs. 49.1 and 23.5 vs. 23.4 mL/min/1.73 m2 in the mild, moderate, and severe CKD groups, respectively. Based on the statistical analysis, eGFR in the mild group had been significantly increased compared to the other groups, whereas there was no considerable difference between the moderate and severe groups.ConclusionsBy the removal of kidney stones, the progression of CKD may be halted. While significant improvement was observed in early-stage CKD, sometimes unexpected deterioration could occur in patients at end stages of renal diseases.کلیدواژه ها
Nephrolithiasis, Renal Insufficiency, Chronic, nephrolithotomy, Percutaneousاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.