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The effect of regular resistance exercise, vitamin D, and calcium supplements on the gastrocnemius muscle in rats in the post-menopausal period: An experimental study

عنوان مقاله: The effect of regular resistance exercise, vitamin D, and calcium supplements on the gastrocnemius muscle in rats in the post-menopausal period: An experimental study
شناسه (COI) مقاله: JR_IJRM-19-3_008
منتشر شده در در سال 1399
مشخصات نویسندگان مقاله:

Seyedeh Zahra Hosseini Sisi - Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Mohammad Ali Azarbayjani - Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Mohammadreza Vafaeenasab - Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Maghsoud Peeri - Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Mohammadreza Dehghani - Yazd Medical Genetic Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

خلاصه مقاله:
Background: Menopause is the natural termination of menstruation which affects the quality and important aspects of womenchr('39')s life. Objective: To evaluate the effect of regular resistance training (Ex) with vitamin D (Vit. D) and calcium (Ca) supplements in the postmenopausal period on muscle tissue in rats. Materials and Methods: In this experimental study, 72 female Wistar rats (8-10-wk old) were randomly divided into control, placebo, Vit. D, Ca, Ex, Ca + Vit. D, Ex + Ca, Ex + Vit. D, and Ex + Ca + Vit. D groups. Control and placebo groups were fed with a standard diet and sesame oil, respectively. Two month after the ovariectomy, Ex, Ca (35 mg/kg), and Vit. D (10000 IU) were administred in all groups except the control. The number of muscle and inflammatory cells, fiber diameter, endomysium thickness, and degenerative collagen fiber area were assessed through hematoxylin-eosin staining. Results: Muscle cell number was increased in the Ex + Vit. D + Ca, Vit. D + Ex, and Vit. D groups compared to the control group; also, inflammatory cell number showed significant increase in the Ex + Vit. D + Ca (12 ± 5.46), Vit. D + Ex (14 ± 3.25), Ex (13 ± 4.08), Vit. D (11 ± 3.26), Ca + Vit. D (10 ± 1.01), and Ca + Ex (9 ± 2.87) groups. Muscle fiber diameter in the Ex + Vit. D + Ca and Vit. D + Ex groups was higher than the other groups. Endomysium thickness was significantly decreased in the Ex + Vit. D + Ca and Vit. D + Ex groups compared to the control and placebo groups (p < 0.001). Degenerative collagen fiber area showed a significant increase in the Ex + Vit. D + Ca and Vit. D + Ex groups (p ≤ 0.001) comparison with the control group. Conclusion: Regular resistance exercise, Vit. D, and Ca supplements can improve muscle morphological features in the postmenopausal period.    

کلمات کلیدی:
Menopause, Muscle, Vitamin D, Calcium, Exercise., یائسگی, عضله, ویتامین D, کلسیم, ورزش.

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1169938/