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Improvement of prediction of RNA's location in the cell by taking advantage of common neural network methods and architectures

عنوان مقاله: Improvement of prediction of RNA's location in the cell by taking advantage of common neural network methods and architectures
شناسه ملی مقاله: IBIS09_025
منتشر شده در نهمین همایش بیوانفورماتیک ایران در سال 1398
مشخصات نویسندگان مقاله:

Negin Sadat Babaiha - Department of Computer and Data Sciences, Faculty of Mathematical Sciences, Shahid Beheshti University, Tehran, Iran
Rosa Aghdam - School of Biological Sciences, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran
Changiz Eslahchi - School of Biological Sciences, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran

خلاصه مقاله:
Process of localization of RNAs at a specific site within the cell is one of the important aspects of the regulation of gene expression [1].The importance of correct intracellular RNA placement in the development of embryonic and neural dendrites has been clearly demonstrated in [2,3]. Improper localization of RNA in the cell—which has been shown to occur due to a variety of reasons, including mutations in trans-regulatory elements—is also associated with the occurrence of some neuromuscular diseases as well as cancer [4].Improvement of our understanding of the intracellular mechanisms of RNA localization can have applications in drug target discovery as well [5].

صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1164287/