Phytochemical study of Nepeta racemosa L.

The Nepeta genus is one of the great genera of the family of mint, accounting for over 250 species of this genus in the world.1This genus was first recognized with two species of N. cataria and N. glechoma. Various types of chemical compounds of this genus have been reported, such as monoterpenes, sesquiuterpenes, dipropenes, triplepenes, flavonoids, phenolic compounds, essential oils, and others.2 Approximately 193 compounds have been identified in the Nepeta species, in which terpenoids and flavonoids are the dominant component of Nepeta. Different species of this genus were used for anti-inflammatory, asthmatic effects, anti-infectious and diuretic effects in traditional medicine.3 N. racemosa L. species in the last survey of Nepeta racemosa, Iran identified 24 chemical compositions including beta-pylene, 4aα, 7α, 7aα-nepetalactone, 4aα, 7α, 7aβ-nepetalactone, 4aβ, 7α, 7aβ-nepetalactone and 8.1-pinole and has been isolated. In this study, N. racemosa L. species was collected from Sabalan mountain and extracted by n-hexane and ethyl acetate. Ursolic acid and oleanolic acid were isolated by column chromatography techniques and identified by 1H-NMR and 13C-NMR. Essential oil of this species was also studied by GC-MS. Major compounds were (E) -β-ocimene, 4aα, 7α, 7aβ-nepetalactone. The total phenol and flavonoid content of the studied species as well as the antioxidant properties were measured using DPPH reagent.

کلیدواژه ها:

Nepeta racemosa L. ، Isolation ، Structure Elucidation ، Total phenol and flavonoidcontent