Design, preparation and characterization of novel core-shell magnetic nanocatalyst based on amino-functionalized calix[4]arenes for one-pot three component synthesis of 2-amino-4H-chromene derivatives

One of the most common phenol-formaldehyde cyclic oligomers from hydroxyalkylation reactions with owning supramolecular chemistry are calixarenes.1 These macrocyclic compounds are qualified to act as synthetic catalysts due to their specific features such as being able to form host-guest complexes and ease of chemical modifications with variety of functions on their rim.2 In this research, a novel magnetic nanocatalyst based on Fe3O4 nanoparticles and their surface modification with different shells particularly the synthetic amino-functionalized calix[4]arene is propounded; as well as, its catalytic activity and considerable performance are evaluated in green and one-pot synthesis of 2-amino-4H-chromene derivatives 4 by utilizing substituted aldehydes 1, dimedone 2 and malononitrile 3 at room temperature and using green solvent, ethanol. This novel magnetic nanocatalyst was characterized by spectroscopic and analytical techniques such as FT-IR, EDX, FE-SEM, VSM, XRD and 1HNMR and also, the solid isolated products were identified by FT-IR, 1HNMR and 13CNMR spectral data.

کلیدواژه ها:

Multicomponent reaction ، Calixarene compounds ، Functionalized magnetic nanoparticles ، 2-amino-4H-chromene derivatives ، Magnetic nanocatalyst