Synthesis and characterization of new derivatives of iminosulfathiazoles

Sulfonamides are a class of antibiotics that have many applications on medicinal. Sulfa drugs have a sulfonamide functional group. Sulfathiazole is one of the most important sulfa drugs that has antibacterial and antimicrobial properties and it can be effective in the treatment of viral and bacterial diseases.1 Azo compounds have attracted much attention in both academic and applied research due to their versatile application in various fields, such as dyeing textile fiber, and advanced application in high technology areas such as laser, liquid crystalline displays, electro-optical devices, and ink-jet printers.2-5Here, the reaction between sulfathiazole and various azo compounds was performed via the imine bond (Fig.1).Then the synthesized products were isolated, purified and the structures of the newly synthesized hybrid molecules were characterized by TLC, M.P., FT-IR, 1H NMR, and 13C NMR. Antibacterial, antioxidant, anticancer properties and other biological properties will also be considered.

کلیدواژه ها:

Sulfathiazole ، Sulfonamide ، Azo compounds