Arylation of aromatic aldehydes in the presence of Cu doped Fe3O4 and phosphine ligand

Metal nanoparticles exhibit excellent optical, electrical, and catalytic properties corresponding bulk materials, especially their high specific surface and surface defects. Among them, magnetic property, separation effect, and the catalytic activity during cyclic utilization of Fe3O4 nanometals are evaluated, indicating they could be used as an efficient degradation catalyst on organic reactions.1 Other hand, copper nanoparticles because of suitable properties such as easy recycling, increasing number of access to the active site and being economically are used as a catalyst in various organic reactions.2 In recent years, many attempts have been attracted to synthesis of diaryl methanol 3 through the addition of alkyl or aryl group to carbonyl groups in the presence of metal catalyst such as copper, silver, palladium, zinc, etc.Addition of organometallic reagents to aldehyde is one of the most important carbon-carbon bond formation, in this work wish to report the 1, 2-arylation of aldehyde 1 by boron reagents 2 in the presence of prepared Cu doped Fe3O4 and phosphine ligands (Scheme 1 and 2).3 The prepared nanomagnetic Cu/Fe3O4 was characterized by scanning electron microscopy, and Fourier transform infrared spectroscopy and the structure of chiral products are investigated by melting point, IR, 1H NMR and 13C NMR spectroscopies.

کلیدواژه ها:

Aldehyde ، Nanomagnetic complex ، Arylation ، Phosphine ligand