One-pot synthesis of tetrahydro-4H-chromene derivatives catalysed by Fe3O4@CNTs@TiO2 nanocomposite

Nanoscience is one of the most prominent research and development areas in modern science. Carbon materials such as carbon nanotubes (CNTs) show great capabilities to serve as substitutes for conventional catalyst or catalyst supports owing to their large surface area.1 Magnetic nanoparticles such as Fe3O4 are often considered to follow the principles of green chemistry.2 Among nanomaterials, TiO2 is a biocompatible and environmentally benign catalyst.3 Heterocyclic compounds are momentous skeleton which widely used for the synthesis of important chemical compounds.4 Among the hetrocycles, functionally substituted 4H-chromenes have recived considerable attention.5 Herein, we report the one-pot synthesis of tetrahydro-4H-chromene derivatives 4 via a three component reactions of aromatic aldehyds 1, malononitrile 2 and dimedone 3 catalysed by Fe3O4@CNTs@TiO2 nanocomposite as a novel, magnetic and recoverable heterogeneous catalyst.

کلیدواژه ها:

tetrahydro-4H-chromenes ، dimedone ، CNTs ، TiO2 ، Fe3O4 ، nanocomposite