Sepideh Habibzadeh - Department of Chemistry, Payame Noor University, Iran

Essential oils have shown promise as antiviral agents against several pathogenic viruses. In this work we hypothesized that essential oil components may interact with key protein targets of the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Molecular docking technique was performed to investigate the probable interactions between two major components of essential oils of Rosa Damascena, geraniol and citronellol, with SARS-CoV-2. From various studies on the SARS-CoV-2 UHSRUWHG LQ the literature, ACE2 receptor with spike RBD has selected as possible drug target. Geraniol and citronellol displayed docking scores of -5.53 kcal/mol and -5.12 kcal/mol respectively.

Covid-19, Rosa Damascena, geraniol, citronellol, molecular docking