Green synthesis of 3-Methyl-4-arylmethylene-isoxazol-5(4H)- ones in magnetized deionized water

Magnetized deionized water (MDW), as a green solvent, was used in the three-component synthesis of 3,4-disubstituted isoxazol-5(4H)-ones under catalyst-free conditions. All reactions carried out in a short period of times and the products are obtained in good-to-high yields. The developed synthetic technique offers numerous advantages including eco-friendly, clean synthesis, simplicity, low-costs, short reaction times, high reaction yields, and easy work-upcompared to the traditional synthetic method

کلیدواژه ها:

Isoxazol-5(4H)-one ، Multi-component reaction ، Catalyst-free ، MDW