Ziba Mosayebi - Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
Mohammadreza Mirzaaghayan - Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
Reza Shabanian - Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
Behdad Gharib - Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran

Background: Neonatal thrombotic diseases can cause mortality or serious morbidity and disability.Case report: In this report, we present a case of neonatal inferior vena cava thromboembolism with several underlyingfactors. Hereditary thrombophilia and genetic mutation in plasminogen activator inhibitor-1 and MTHFR A1298C genesin conjunction with cleft palate resulted in poor lactation and hypernatremic dehydration. A peripherally insertedcentral catheter in the inferior vena cava was an additional underlying factor. Thrombosis mass was dislodged to theright atrium while asymptomatic and accidentally detected during routine echocardiography.Conclusion: Surgical thrombectomy was done successfully, and the mass was removed from the right atrium.

Hereditary thrombophilia, Hypernatremic dehydration, Neonatal Thrombosis, Peripherally Inserted Central Catheter