The Effects of Medicinal Plants on Pancreatic Beta Cells in Diabetes: A Systematic Review of Iranians’ Contributions

  • سال انتشار: 1399
  • محل انتشار: مجله پزشکی بالینی، دوره: 7، شماره: 1
  • کد COI اختصاصی: JR_RCM-7-1_007
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 468
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نویسندگان

Davood Oliaee

Faculty of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran.

Hamid Reza Niazkar

Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran.

Abbasali Abbasnezhad

Department of Physiology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.

Mohammad Ghorbani

Department of Hematology and Blood banking, Faculty of medicine, Gonabad University of Medical Sciences, Gonabad. Iran.

چکیده

Introduction: Diabetes mellitus (DM) is a metabolic disorder with a high prevalence, which affects approximately ۲۵% of the world’s population. This systematic review aimed to assess the Iranian research regarding the effects of medicinal plants on pancreatic beta cells in diabetes.Methods: This systematic review was conducted via searching in databases such as Medline, PubMed, Google Scholar, and ScienceDirect until April ۲۰۱۸. The studied that were published in Iran, peer-reviewed, and designed as a randomized control trial on type I diabetes were retrieved and screened.Result: The initial search results of the electronic databases yielded ۸۲۲ relevant articles. After two stages of screening, checking the references, and removing the duplicate articles in various databases, ۱۸ articles were finally selected for the review.Conclusion: According to the results, medicinal plants have a positive impact on the performance of pancreatic beta cells in animal models through various mechanisms, such as increasing the number, size, regeneration, and reduction of the inflammation of beta cells.

کلیدواژه ها

Diabetes Mellitus, Medical Herbssyndrome, Medical plants, Pancreatic Beta Cells

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