Ultrasound-assisted removed of naproxen using magnetic polyurethane nanofibers

Magnetic polyurethane (PU) nanofibers were synthesized by an electrospinning technique and applied for removing of naproxen from aquatic and biological samples. Magnetic polyurethane (PU) nanofibers were electrospun using a PU polymer solution containing the dispersed magnetic nanoparticles. The magnetic properties of iron nanoparticles, along with the use of an electrospinning technique, led to the formation of a suitable sorbent toward removing of naproxen. Magnetic polyurethane (PU) nanofibers could be subsequently removed from the sample solution by applying a permanent magnet. The scanning electron microscopy (SEM) image of the magnetic PU nanofibers confirms that their diameters are in the range of 45–125 nm. The major parameters influencing the morphology of the magnetic PU nanofibers, comprising the weight ratio of iron and PU components, the applied voltage and the coating time, were optimized. Moreover, parameters including the amount of sorbent, extraction time, pH and salinity of aqueous samples were considered for optimization. Our results show that under optimized condition, high naproxen removal up to 99% can be achieved.The removing of naproxen 1000 ppm was performed using 30 mg of magnetic polyurethane (PU) nanofibers in the ultrasonic system. GC-MS analyses of the eluting solvent indicated that initial total naproxen was removing and transferring in acetonitrile phase. Acetonitrile was reported as a good extractant solvent. The whole procedure proved to be conveniently rapid, efficient and economical to removing naproxen from environmental and biological samples. Eventually, the developed method was applied to the analysis of water, urine, milk and plasma samples and relative recoveries of 76 to 99% were achieved.

کلیدواژه ها:

Magnetic polyurethane (PU) nanofibers ، Biological samples ، Removing ، Naproxen