Alkylation and cyanation of thiophene as a substance with plentiful biological properties
عنوان مقاله: Alkylation and cyanation of thiophene as a substance with plentiful biological properties
شناسه ملی مقاله: IRCCE06_010
منتشر شده در ششمین کنفرانس بین المللی شیمی و مهندسی شیمی در سال 1398
شناسه ملی مقاله: IRCCE06_010
منتشر شده در ششمین کنفرانس بین المللی شیمی و مهندسی شیمی در سال 1398
مشخصات نویسندگان مقاله:
Mehran Ghasemi - Faculty of Chemistry, Kharazmi University, No. ۴۳. Mofateh Street, Enghelab Ave., ۱۵۷۱۹-۱۴۹۱۱ Tehran, Iran
Azizollah Habibi - Faculty of Chemistry, Kharazmi University, No. ۴۳. Mofateh Street, Enghelab Ave., ۱۵۷۱۹-۱۴۹۱۱ Tehran, Iran
خلاصه مقاله:
Mehran Ghasemi - Faculty of Chemistry, Kharazmi University, No. ۴۳. Mofateh Street, Enghelab Ave., ۱۵۷۱۹-۱۴۹۱۱ Tehran, Iran
Azizollah Habibi - Faculty of Chemistry, Kharazmi University, No. ۴۳. Mofateh Street, Enghelab Ave., ۱۵۷۱۹-۱۴۹۱۱ Tehran, Iran
Thiophene is a hetrocycle with high biological and pharmaceutical activity. Double functionalization of this compounds in one pot is one of the exciting challenges. In this study, using the Catellani strategy, it has been attempted to cyanation and alkylation the positions 2 and 3 of thiophene, respectively. One of the benefits of this reaction is the C-H activation of position 3 of thiophene followed by the formation of two carbon-carbon bonds in one pot.
کلمات کلیدی: Thiophene, C-H activation, Catellani raction, Cyanation
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1005743/